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Nov 28, 2022

The pharmacological effects of elderberry fruit extract


Part1. What is elderberry fruit extract?

Elderberry extract is extracted from the stems and branches of Sambucus williamsii Hance., a plant of Lonicaceae, and contains active ingredients such as phenolic acids and triterpene aglycones. It has pharmacological activities such as anti-osteoporosis, promotion of fracture healing, anti-inflammation, anti-virus, anti-oxidation, and improvement of immune activity. It is widely used in cosmetics and has the functions of moisturizing the skin and beautifying the skin. The ingredients such as elderberry glycosides and mucilaginous substances have the functions of sterilization, anti-inflammatory and anti-itching. It can be used in daily necessities for shampoo and hair care.


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Part2. Chemical Composition

At present, triterpene aglycone compounds such as ursolicacid, oleanolic acid, α-myssinol, betulin, betulinic acid, and azadirachtin are isolated from elderberry stems; β-sitosterol, stigmasterol, carotin, dandelion Alcohol and other sterol compounds; and vanillin, vanillyl ethyl ketone, coniferous aldehyde, syringaldehyde, p-hydroxybenzoic acid, 4-hydroxycinnamic acid, protocatechuic acid and other phenolic acid compounds. In addition, it also contains flavonoids, lignans and sterols.


Part3. Pharmacological effects

1. Anti-osteoporosis and promote fracture healing

Studies have shown that the chloroform extraction layer of 60% ethanol crude extract of elderberry has a significant effect on the restoration of bone density, and contributes to the bone growth and bone content of the femur and tibia.

2. Anti-inflammatory and analgesic

Elderberry stems have obvious analgesic and anti-inflammatory effects.

3. Anti-bacteria, virus

The results of the study showed that larch resinol isolated from the methanol extract of elderberry stems exhibited its antifungal activity by interfering with the cell membrane of fungi, and it may be used as a new type of antifungal agent for the treatment of human fungal infections.

4. Anticancer effect

Elderberry oil has certain anticancer effects.

5. Improve learning and memory ability

It can improve learning and memory ability, and its improvement effect is equal to or better than Naofukang.

6. Anti-AIDS

Elderberry extract has inhibitory effect on HIV-1 reverse transcriptase when IC50 is 0.017g/L, indicating that it has anti-AIDS activity.

7. Blood lipid lowering effect

Oral administration of elderberry oil has obvious effects of lowering blood fat and anti-arteriosclerosis, and its effect of lowering blood fat and anti-arteriosclerosis is superior to that of Maitong.


elderberry fruit extract1

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